Year 2018 / Volume 25 / Number 5

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Hyponatremia severe as a result of the association of a thiazide diuretic in a patient with long-term therapy with oxcarbazepine.

Rev. Soc. Esp. Dolor. 2018; 25(5): 301-302 / DOI: 10.20986/resed.2017.3527/2016

Tamara Rivero Salvador, Clara Marín Zaldivar, Pablo Baltanas Rubio, Raquel Murillo Pina, María del Pilar Aguelo Asensio, Beatriz Ruiz Torres, Marta Pedraz Natalias


ABSTRACT

Oxcarbazepine acts primarily trough its active metabolite MHD, with a lower potencial for side effects than carbamazepine. However, presents higher incidence of hyponatremia (2,7%), dosis dependent.



RESUMEN

La oxcarbazepina actúa principalmente a través de su metabolito activo MHD, por lo que presenta menor número de efectos secundarios que la carbamazepina. Sin embargo, presenta mayor tendencia a la hiponatremia (2,7 %), dosis dependiente.


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Rivero Salvador T, Marín Zaldivar C, Baltanas Rubio P, Murillo Pina R, Aguelo Asensio M, Ruiz Torres B, et all. Hyponatremia severe as a result of the association of a thiazide diuretic in a patient with long-term therapy with oxcarbazepine.. Rev Soc Esp Dolor 2018; 25(5): 301-302 / DOI: 1020986/resed20173527/2016


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Publication history

Received: 29/10/2016

Accepted: 31/10/2016

Online First: 04/01/2017

Published: 03/10/2018

Article Online First time: 67 days

Article editing time: 704 days


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