Rev. Soc. Esp. Dolor. 2019; 26(3): 184-198 / DOI: 10.20986/resed.2019.3733/2019
                                    Julio Rotondo, Martín Toro, Marcos Bolívar, María  Eugenia Seijas, Carmen Carrillo
                                    
                                    
                                    ABSTRACT
Parkinson's disease (PD) is a neurodegenerative disease, the second most prevalent, after Alzheimer's disease. It presents both motor and non-motor symptoms; These include autonomic dysfunction, unexplained pain, cognitive impairment, anxiety, depression, among others. Some of these patients experience pain as an early symptom of Parkinson's, even before the expression of their disease. Among people who have PD and who experience pain, they describe it as a worrisome symptom, being a cause of suffering and disability. However, despite this, pain in PD often remains undiagnosed and untreated. Therefore, it is important to understand that pain can be part of the Parkinson's experience and learn ways to manage it.
This paper reviews current data on possible mechanisms, classifications, evolution, potential risk factors and pain control in PD. The mechanism of pain in this situation is complex, and is influenced by different factors, which may be linked to pathological changes in the anatomical structures involved in nociceptive mechanisms.
RESUMEN
La enfermedad de Parkinson (EP) es una enfermedad neurodegenerativa, la segunda con mayor prevalencia después de la enfermedad de Alzheimer. Presenta tanto síntomas motores como no motores; entre estos últimos se encuentran disfunción autonómica, dolor inexplicable, deterioro cognitivo, ansiedad, depresión, entre otros. Algunos de estos pacientes experimentan el dolor como un síntoma temprano de Parkinson, incluso antes de la expresión de su enfermedad. Entre las personas que tienen EP y que experimentan dolor, lo describen como un síntoma preocupante, siendo una causa de sufrimiento y de incapacidad. Sin embargo, a pesar de ello, el dolor en la EP a menudo permanece sin diagnóstico y sin tratamiento. Por tanto, es importante entender que el dolor puede ser parte de la experiencia del Parkinson y aprender las formas de manejarlo.
Este trabajo revisa datos actuales sobre posibles mecanismos, clasificaciones, evolución, factores de riesgo potenciales y control del dolor en la EP. El mecanismo del dolor en esta situación es complejo, y está influenciado por distintos factores, pudiendo estar vinculado a cambios patológicos en las estructuras anatómicas involucradas en mecanismos nociceptivos.
                                    
                                    
                                    
                                    
	
                                        
                                        
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                                                            19/06/2025 16:12:47
                                                            My first ALS  symptom occurred in 2016, but was diagnosed in 2018. I had severe symptoms ranging from shortness of breath, balance problems, couldn't walk without a walker or a power chair, i had difficulty swallowing and fatiue. I was given medications which helped but only for a short burst of time, then I decided to try alternative measures and began on ALS Formula treatment from Aknni herbs centre, It has made a tremendous difference for me (Visit ww w. aknniherbscentre.c om). I had improved walking balance, increased appetite, muscle strength, improved eyesight and others.
                                                        
                                                        
                                                    
                                                        
                                                            29/05/2025 10:05:42
                                                            In 2019, I began experiencing symptoms of Parkinson's disease, which was diagnosed in 2021. Among my severe symptoms were tremors, difficulty walking, weakness throughout my body, and stiffness and rigidity. My meds only provided temporary relief, so I decided to try other approaches and started the PD-5 treatment program from uinehealthcentre. net. With the help of this therapy regimen, I have seen significant improvements in my walking, balance, tremors, and appetite, and I have resumed my guitar playing again and sign my name as I had before Parkinson's. I am incredibly grateful.
                                                        
                                                        
                                                    
                                                
                                                
	
                                             
                                         
                                    
 
                                 
                                
                                
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