Year 2021 / Volume 28 / Supplement 1

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Article Osteoarthritis Monographic

Intra-articular botulinum toxin and ozone in osteoarthritis

Rev. Soc. Esp. Dolor. 2021; 28(13): 73-79 / DOI: 10.20986/resed.2021.3857/2020

Daniel Samper


ABSTRACT

Osteoarthritis pain continues to be one of the main causes of medical visit due to the insufficient efficacy of established treatments, therefore, the need arises to search for new therapies that improve the analgesic response.
Intra-articular injection of botulinum toxin and/or medicinal ozone are two of the new options to consider in this pathology.
We develop in this chapter a review of the management of these two analgesic options.



RESUMEN

El dolor por osteoartrosis continúa siendo una de las principales causas de consulta médica debido a la insuficiente eficacia de los tratamientos establecidos, y por ello surge la necesidad de buscar nuevas terapias que mejoren la respuesta analgésica.
La inyección intrarticular de toxina botulínica y/o de ozono medicinal son dos de las nuevas opciones a considerar en esta patología.
Realizamos en este capítulo una revisión del manejo de estas dos opciones analgésicas.





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Bibliografía

1. Barash JR, Arnon SS. A novel strain of Clostridium botulinum that produces type B and type H botulinum toxins. J Infect Dis. 2014;209(2):183-91. DOI: 10.1093/infdis/jit449.
DOI: 10.1093/infdis/jit449
2. Burgen ASV, Dickens F, Zatman LJ. The action of botulinum toxin on the neuro-musuclar junction. J Psysiol (Lond) 1949;109(1-2):10-24. DOI: 10.1113/jphysiol.1949.sp004364.
DOI: 10.1113/jphysiol.1949.sp004364
3. Scott AB. Botulisnum toxin injection into extraocular muscles as an alternative to strabismus surgery. J Pedaitr Ophtalmol Strabismus. 1980;17(1):21-5.
DOI: 10.3928/0191-3913-19800101-06
4. Safarpur Y, Jabbari B. Botulinum toxin treatment of movement disorders. Curr Treat Options Neurol. 2018;20(2):4. DOI: 10.1007/s11940-018-0488-3.
DOI: 10.1007/s11940-018-0488-3
5. Jackson JL, Kuriyama A, Hayashino Y. Botulinum toxin A for prophylactic treatment of migraine and tension headaches in adults: A meta-analysis. JAMA. 2012;307(16):1736-45. DOI: 10.1001/jama.2012.505.
DOI: 10.1001/jama.2012.505
6. Herd CP, Tomlinson CL, Rick C, Scotton WJ, Edwards J, Ives N, et al. Botulinum toxins for the prevention of migraine in adults. Cochrane Database Syst Rev. 2018;6(6):CD011616. DOI: 10.1002/14651858.CD011616.pub2.
DOI: 10.1002/14651858.CD011616.pub2
7. Montecucco C, Molgo J. Botulinal neurotoxins: Revival of an old killer. Curr Opin Pharmacol. 2005;5(3):274-9. DOI: 10.1016/j.coph.2004.12.006.
DOI: 10.1016/j.coph.2004.12.006
8. Mahowald ML, Singh JA,Dykstra D. Long term effects of intra-articular botulinum toxin A for refractory joint pain. Neurotox Res. 2006;9(2-3):179-88. DOI: 10.1007/BF03033937.
DOI: 10.1007/BF03033937
9. Cheshire WP, Abashian SW, Mann JD. Botulinum toxin in the treatment of myofascial pain syndrome. Pain 1994;59(1):65-9. DOI: 10.1016/0304-3959(94)90048-5.
DOI: 10.1016/0304-3959(94)90048-5
10. Gobel H. Botulinum toxin A in pain management: mechanisms of action and rationales for optimum use. Pain Headache. 2003;14:4-22.
11. Welch MJ, Purkiss JR, Foster KA. Sensitivity of embryonic rat dorsal root ganglia neurons to Clostridium botulinum neurotoxins. Toxicon. 2000;38(2):245-58. DOI: 10.1016/s0041-0101(99)00153-1.
DOI: 10.1016/S0041-0101(99)00153-1
12. Durham PL, Cady R, Cady R. Regulation of calcitonin gene-related peptide secretion from trigeminal nerve cells by botulinum toxin type A: Implications for migraine therapy. Headache. 2004;44(1):35-42, discussion 42-43. DOI: 10.1111/j.1526-4610.2004.04007.x.
DOI: 10.1111/j.1526-4610.2004.04007.x
13. Meng J, Wang J, Lawrence G, Dolly JO. Synaptobrevin I mediates exocytosis of CGRP from sensory neurons and inhibition by botulinum toxins reflects their anti-nociceptive potential. J Cell Sci. 2007;120(Pt 16):2864-74. DOI: 10.1242/jcs.012211.
DOI: 10.1242/jcs.012211
14. Cheng J, Liu W, Duffney LJ, Yan Z. SNARE proteins are essential in the potentiation of NMDA receptors by group II metabotropic glutamate receptors. J. Physiol. 2013;591(16):3935-47. DOI: 10.1113/jphysiol.2013.255075.
DOI: 10.1113/jphysiol.2013.255075
15. Morenilla-Palao C, Planells-Cases R, Garcia-Sanz N, Ferrer-Montiel A. Regulated exocytosis contributes to protein kinase C potentiation of vanilloid receptor activity. J Biol Chem. 2004;279(24):25665-72. DOI: 10.1074/jbc.M311515200.
DOI: 10.1074/jbc.M311515200
16. Mahowald ML, Singh JA, Goelz E, Kushnaryov A, Krug HE. Intra-articular botulinum toxin type A: A new approach to treat arthritis joint pain. In: American College of Rheumatology Annual meeting; 2007. p. Abs 1688.
17. Singh JA, Mahowald ML, Noorbaloochi S. Intra-arti- cular botulinum toxin A for refractory shoulder pain: a randomized, double-blinded, placebo-controlled trial. Transl Res. 2009;153(5):205-16. DOI: 10.1016/j.trsl.2009.02.004.
DOI: 10.1016/j.trsl.2009.02.004
18. Dykstra DD, Stuckey MW, Schimpff SN, Singh JA, Mahowald ML. Use of botulinum toxins for chronic headaches: a focused review. Pain Clin. 2007;19:27-32.
DOI: 10.1179/016911107X217473
19. Fenollosa P, Izquierdo RM, Canós MA, Pallarés J. Efectos de la toxina botulínica A (Botox) intraarticular en la artrosis de rodilla avanzada. Rev Soc Esp Dolor. 2011;18(6):320-5.
20. Bahman J, Machado D. Treatment of refractory pain with botulinum toxins-An evidence -based review. Pain Medicine 2011;12(11):1594-606. DOI: 10.1111/j.1526-4637.2011.01245.x.
DOI: 10.1111/j.1526-4637.2011.01245.x
21. Wong SM, Hui Ac, Tong PY. Treatment of lateral epicondylitis with botulinum toxin: A randomized, double blind, placebo-controlled trial. Ann Intern Med. 2005;143(11):793-7. DOI: 10.7326/0003-4819-143-11-200512060-00007.
DOI: 10.7326/0003-4819-143-11-200512060-00007
22. Hayton MJ, Santini AJ, Hughes PJ, Frostick SP, Trail IA, Stanley JK. Botulinum toxin injection in the treatment of tennis elbow. A double-blind, randomized, controlled, pilot study. J Bone Joint Surg Am. 2005;87(3):503-7. DOI: 10.2106/JBJS.D.01896.
DOI: 10.2106/JBJS.D.01896
23. Placzek R, Drescher W, Deuretzbacher G, Hempfing A, Meiss AL. Tretament of chronic radial epicondylitis with botulinum toxin A. A double-blind, placebo-controlled, randomized multicenter study. J Bone Joint Surg Am. 2007;89(2):255-60. DOI: 10.2106/JBJS.F.00401.
DOI: 10.2106/JBJS.F.00401
24. Espandar R, Heidari P, Rasouli MR, Saadat S, Farzan M, Rostami M, et al. Use of anatomic measurement to guide injection of botulinum toxin for the management of chronic lateral epicondylitis: A randomized controlled trial. CMAJ. 2010;182(8):768-73. DOI: 10.1503/cmaj.090906.
DOI: 10.1503/cmaj.090906
25. Singh J, Mahowald M, Noorbaloochi S. Intra-articular botulinum toxin A for refractory shoulder pain: a randomized, double-blinded, placebo-controlled trial. Transl Res. 2009;153(5):205-16. DOI: 10.1016/j.trsl.2009.02.004.
DOI: 10.1016/j.trsl.2009.02.004
26. Joo YJ, Yoon SJ, Kim CW, Lee JH, Kim YJ, Koo JH, et al. A comparison of the short-term effects of a botulinum toxin type A and triamcinolone acetate injection on adhesive capsulitis of the shoulder. Ann Rehabil Med. 2013;37(2):208-14. DOI: 10.5535/arm.2013.37.2.208.
DOI: 10.5535/arm.2013.37.2.208
27. Durán-Hernández S, Soto-Rodríguez JF, Allen-Bobadilla J, Durán Hernández N, García-Mosco P. Tratamiento conservador de la osteoartrosis de cadera con toxina botulínica tipo A. Gac Med Mex. 2019;155(Suppl 1):S56-S61. DOI: 10.24875/GMM.19005151.
DOI: 10.24875/GMM.19005151
28. Bonn A, Smith J, Dahm D, Sorenson E, Larson D, Fitz-Gibbon P, et al. Efficacy of intra-articular botulinum toxin type A in painful knee osteoarthritis: a pilot study. PM R 2010;3(4):268-76. DOI: 10.1016/j.pmrj.2010.02.011.
DOI: 10.1016/j.pmrj.2010.02.011
29. Hsieh L, Wu Ch. Effects of botulinum toxin landmark-guided intra-articular injection in subjects with knee osteoarthritis. PMR 2016;8(12):1127-35. DOI: 10.1016/j.pmrj.2016.05.009.
DOI: 10.1016/j.pmrj.2016.05.009
30. McAlindon TE, Schmidt U, Bugarin D, Abrams S, Geib T, DeGryse RE, et al. Efficacy and safety of single-dose onabotulinumtoxinA in the treatment of symptoms of osteoarthritis of the knee: results of a placebo-controlled, double blind study. Osteoarthritis Cartilage. 2018(26):1291-9. DOI: 10.1016/j.joca.2018.05.001.
DOI: 10.1016/j.joca.2018.05.001
31. Shukla D, Sreedhar S, Rastogi V. A comparative study of botulinum toxin: A con triamcinolone compared to triamcinolone alone in the treatment of osteoarthritis of knee. Anesth Essays Res. 2018;12(1):47-9. DOI: 10.4103/aer.AER_210_17.
DOI: 10.4103/aer.AER_210_17
32. Bao X, Tan J, Flyzik M, Ma X, Liu H, Liu H. Effect of therapeutic exercice on knee osteoarthritis after intra-articular injection of botulinum toxin type A, hyaluronidate or saline: a randomized controlled trial. J Rehabil Med. 2018;50(6):534-41. DOI: 10.2340/16501977-2340.
DOI: 10.2340/16501977-2340
33. Mendes JG, Natour J, Nunes-Tamashiro JC, Toffolo SR, Rosenfeld A, Furtado RNV. Comparison between intra-articular Botulinum toxin type A, corticosteroid, and saline in knee osteoarthritis: a randomized controlled trial. Clinical Rehabilitation. 2019;33(6):1015-1026. DOI: 10.1177/0269215519827996.
DOI: 10.1177/0269215519827996
34. Wu T, Song H, Dong Y, Ye Y, Li J. Intra-articular injections of botulinum toxin a for refractory joint pain: a systematic review and meta-analysis. Clin Rehabil. 2017;31(4):435-43. DOI: 10.1177/0269215516644951.
DOI: 10.1177/0269215516644951
35. Courseau M, Vergne P, Ranoux D, Lachatre A. Efficacy of intra-articular botulinum toxin in osteoarticular joint pain: a meta-analysis of randomized controlled trials. Clin J Pain. 2018;34(4):383-9. DOI: 10.1097/AJP.0000000000000538.
DOI: 10.1097/AJP.0000000000000538
36. Safarpour Y, Jabbari B. Botulinum toxin treatment of pain syndromes- an evidence based review. Toxicon 2018;147:120-8. DOI: 10.1016/j.toxicon.2018.01.017.
DOI: 10.1016/j.toxicon.2018.01.017
37. Zhai S, Huang B, Yu K. The efficacy and safety of botulinum toxin type A in painful knee osteoarthritis: a systematic review and meta-analysis. J Int Med Res. 2019;48(4):300060519895868. DOI: 10.1177/0300060519895868.
DOI: 10.1177/0300060519895868
38. Kolasinski S, Neogi T, Hochberg M, Oatis C, Guyatt G, Block J, et al. 2019 American College of Reumathology/Arthritis Foundation guideline for the management of osteoarthritis of the hand, hip and knee. Arthritis Care Res. 2020;72(2): 149-62. DOI: 10.1002/acr.24131.
DOI: 10.1002/acr.24131
39. Bocci V. General mechanisms of action of ozone therapy and mechanisms in pain treatment. Rev Soc Esp Dolor. 2005;12(Supl. II):24-36.
40. Hidalgo-Tallón FJ, Torres LM. Ozonoterapia en medicina del dolor. Revisión. Rev Soc Esp Dolor. 2013;20(6):291-300.
DOI: 10.4321/S1134-80462013000600003
41. Bocci V, Corradeschi F. Studies on the biological effects of ozone: III and attempt to define conditions for optimal induction of cytokines. Lymphokine Cytokine Res 1993;12(2):121-6.
42. Bocci V. Mecanismos de acción generales de la ozonoterapia y mecanismos en el tratamiento del dolor. Rev Soc Esp Dolor. 2005;12(Supl. II):24-36.
43. Viebahn-Haensler R. Milestones of medical ozone. Rev Soc Esp Dolor. 2005;12(Supl. II):3-9.
44. De Lucas JC. Peripheral infiltrations with ozone. Indications, techniques and clinical experience. Rev Soc Esp Dolor. 2005;12(Supl. II):37-47.
45. Seyam O, Smith N, Reid I, Gandhi J, Jiang W, Ali S. Clinical utility of ozone therapy for musculoskeletal disorders. Med Gas Res. 2018;8(3):103-10. DOI: 10.4103/2045-9912.241075.
DOI: 10.4103/2045-9912.241075
46. Al-Jaziri A, Mahmoodi S. Painkilling effect of ozone-oxygen injection on spine and joint osteoarthritis. Saudi Med J. 2008;29(4):553-7.
47. Li JH, Zhou LX, Li GY, Cheng B. Treatment of middle-aged and aged patients with knee osteoarthritis of yang-deficiency induced cold-damp syndrome by ozone combined Chinese materia medica: a clinical research Chin J Int Trad West Med. 2013;33(4):471-5.
48. Samper D, Rovira G, Monerris M, González M, Mazo V. Tratamiento de la gonalgia por gonartrosis con ozono intrarticular. Rev Soc Esp Dolor. 2013;20(3):107-12.
DOI: 10.4321/S1134-80462013000300002
49. Babaei-Ghazani A, Najarzadeh S, Mansoori K, Forough B, Pezhman S, Ebadi S, et al. The effects of ultrasound-guided corticosteroid injection compared to oxygen-ozone (O2-O3) injection in patients with knee osteoarthritis: a randomized controlled trial. Clinical Reumatology. 2018;37:2517-27.
DOI: 10.1007/s10067-018-4147-6
50. Feng X, Beiping L. Therapeutic efficacy of ozone injection into the knee for the osteoarthritis patient along with oral celecoxib and glucosamine. J Clin Diagn Res. 2017;11(9):UC01-UC03. DOI: 10.7860/JCDR/2017/26065.10533.
DOI: 10.7860/JCDR/2017/26065.10533
51. Lopes de Jesus C, dos Santos F, Oliveira L, Monteiro I, Sousa M, Fernandes V. Comparison between intra-articular ozone and placebo in the treatment of knee osteoarthritis: A randomized, double-blinded, placebo-controlled study. PLoS ONE. 2017;12(7):e0179185. DOI: 10.1371/journal.pone.0179185.
DOI: 10.1371/journal.pone.0179185
52. Mutlu T, Mutlu S, Dernek B, Komur B, Aydogmus S, Nur F. Choice of intra-articular injection in treatment of knee osteoarthritis: platelet-rich plasma, hyaluronic acid or ozone options. Knee Surg Traumatol Arthrosc. 2017;25(2):485-92. DOI: 10.1007/s00167-016-4110-5.
DOI: 10.1007/s00167-016-4110-5
53. Fernández-Cuadros M, Pérez-Moro O, Albajadejo-Florin MJ, Álava-Rabasa S. El ozono intrarticular modula la inflamación, mejora el dolor, la rigidez, la función y tiene un efecto anabólico sobre la artrosis de rodilla: estudio cuasiexperimental prospectivo tipo antes-después, 115 pacientes. Rev Soc Esp. Dolor 2020;27(2):78-88.
54. Ukusoy G, Bilge A, Öztürk Ö. Comparison of corticosteroid injection and ozone injection for relief of pain in chronic lateral epicondylitis. Acta Orthop Belg. 2019;85(3):317-24.
55. Hedayatabad J, Kachooei A, Chaharjouy N, Varizi N, Mehrad-Majd H, Emadzadeh M, et al. The effect of ozone (O3) versus hyaluronic acid on pain and function in patients with knee osteoarthritis: A Systematic review and meta-analysis. Arch Bone Jt Surg. 2020;8(3):343-54. DOI: 10.22038/abjs.2020.46925.2292.
56. Noori-Zadeh A, Bakhtiyari S, Khooz R, Haghani K, Darabi S. Intra-articular ozone therapy efficiently attenuates pain in knee osteoarthritic subjects: A systematic review and meta-analysis. Complement Ther Med. 2019;42:240-7. DOI: 10.1016/j.ctim.2018.11.023.
DOI: 10.1016/j.ctim.2018.11.023
57. Souza C, Respizzi S, Virelli L, Vandenbulcke F, iacono F, Kon E, et al. Oxygen-Ozone therapy for the treatment of knee osteoarthritis: A systematic review of randomized controlled trials. Arthroscopy. 2020;36(1):277-86. DOI: 10.1016/j.arthro.2019.05.043.
DOI: 10.1016/j.arthro.2019.05.043
58. Palanca I, Puig MM, Elola J, Bernal JL, Paniagua JL, Grupo de Expertos. Unidad de tratamiento de dolor: estándares y recomendaciones. Madrid: Ministerio de Sanidad, Política Social e Igualdad; 2011.

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Instrucciones para citar

Samper D. Intra-articular botulinum toxin and ozone in osteoarthritis. Rev Soc Esp Dolor 2021; 28(13): 73-79 / DOI: 1020986/resed20213857/2020


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